Personality Disorder, also known as enduring personality change after psychiatric illness, is related to schizotypal personality disorder and schizoid personality disorder, and has symptoms including sleep disturbances, photophobia and personality changes. An important gene associated with Personality Disorder is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Methylphenidate and Risperidone have been mentioned in the context of this disorder. Affiliated tissues include brain and prefrontal cortex, and related phenotypes are shRNA abundance <= 50% and nervous system