Periosteal Osteogenic Sarcoma

Periosteal Osteogenic Sarcoma, also known as periosteal osteosarcoma, is related to chondrosarcoma and parosteal osteosarcoma. An important gene associated with Periosteal Osteogenic Sarcoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways are Defective EXT1 causes exostoses 1, TRPS2 and CHDS and 11p11.2 copy number variation syndrome. Affiliated tissues include bone and bone marrow, and related phenotypes are Decreased shRNA abundance and Decreased p24 protein expression