Presbyopia, also known as accommodation insufficiency of old age, is related to oculodentodigital dysplasia and eye disease, and has symptoms including aniseikonia An important gene associated with Presbyopia is MIP (Major Intrinsic Protein Of Lens Fiber), and among its related pathways/superpathways is 1q21.1 copy number variation syndrome. The drugs Vitamins and Mitomycins have been mentioned in the context of this disorder. Affiliated tissues include eye and breast, and related phenotype is vision/eye.