Proprotein Convertase 1/3 Deficiency (PC1 DEFICIENCY)

Proprotein Convertase 1/3 Deficiency, also known as obesity due to prohormone convertase i deficiency, is related to central diabetes insipidus and hypothyroidism, and has symptoms including diarrhea An important gene associated with Proprotein Convertase 1/3 Deficiency is PCSK1 (Proprotein Convertase Subtilisin/Kexin Type 1), and among its related pathways/superpathways are Growth hormone receptor signaling and Alstrom syndrome. Affiliated tissues include small intestine and pituitary, and related phenotypes are obesity and increased adipose tissue