Purpura Fulminans

Purpura Fulminans, also known as purpura gangrenosa, is related to protein c deficiency and protein s deficiency. An important gene associated with Purpura Fulminans is PROC (Protein C, Inactivator Of Coagulation Factors Va And VIIIa), and among its related pathways/superpathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. The drugs Protein S and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and homeostasis/metabolism