Peripheral Vascular Disease, also known as peripheral arterial disease, is related to raynaud disease and diabetic angiopathy, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Peripheral Vascular Disease is APOB (Apolipoprotein B), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Azithromycin and Roxithromycin have been mentioned in the context of this disorder. Affiliated tissues include Bone, bone marrow and heart, and related phenotypes are Increased free cholesterol and Reduced mammosphere formation