Paraplegia, also known as paraplegia, lower, is related to spastic paraplegia 48, autosomal recessive and spastic paraplegia 15, autosomal recessive, and has symptoms including hemiplegia, ophthalmoplegia and paraparesis. An important gene associated with Paraplegia is SLC33A1 (Solute Carrier Family 33 Member 1). The drugs Acetylcholine and Dronabinol have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain, and related phenotypes are nervous system and growth/size/body region