Periapical Granuloma, also known as apical granuloma, is related to chronic apical periodontitis and periapical periodontitis. An important gene associated with Periapical Granuloma is TNFSF11 (TNF Superfamily Member 11), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Calcium, Dietary and Calcium have been mentioned in the context of this disorder. Affiliated tissues include endothelial and bone, and related phenotypes are homeostasis/metabolism and cellular