Prion Disease, also known as transmissible spongiform encephalopathies, is related to creutzfeldt-jakob disease and gerstmann-straussler disease. An important gene associated with Prion Disease is PRNP (Prion Protein (Kanno Blood Group)), and among its related pathways/superpathways are Alzheimer's disease and miRNA effects and Neuroscience. The drugs Coal tar and Quinacrine have been mentioned in the context of this disorder. Affiliated tissues include brain and cortex, and related phenotypes are nervous system and endocrine/exocrine gland