Pernicious Anemia

Pernicious Anemia, also known as anemia, pernicious, is related to congenital intrinsic factor deficiency and gastritis, and has symptoms including fatigue An important gene associated with Pernicious Anemia is CBLIF (Cobalamin Binding Intrinsic Factor), and among its related pathways/superpathways are Cobalamin (Cbl, vitamin B12) transport and metabolism and Methotrexate Pathway (Cancer Cell), Pharmacodynamics and Pharmacokinetics. The drugs Hydroxocobalamin and Cyanocobalamin have been mentioned in the context of this disorder. Affiliated tissues include tongue and skin, and related phenotypes are megaloblastic anemia and malabsorption of vitamin b12