Primary Bone Dysplasia

Primary Bone Dysplasia, also known as primary skeletal dysplasia, is related to high bone mass osteogenesis imperfecta and thanatophoric dysplasia, type i. An important gene associated with Primary Bone Dysplasia is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Signaling by Receptor Tyrosine Kinases. Affiliated tissues include bone and tongue, and related phenotypes are homeostasis/metabolism and nervous system