Premature Aging Syndrome, Penttinen Type (PENTT)

Premature Aging Syndrome, Penttinen Type, also known as acroosteolysis-keloid-like lesions-premature aging syndrome, is related to premature aging and progeroid syndrome. An important gene associated with Premature Aging Syndrome, Penttinen Type is PDGFRB (Platelet Derived Growth Factor Receptor Beta). Affiliated tissues include skin and skeletal muscle, and related phenotypes are prematurely aged appearance and osteolytic defects of the distal phalanges of the hand