Primary Interstitial Lung Disease Specific to Childhood Due to Pulmonary Surfactant Protein Anomalies, also known as primary ild specific to childhood due to pulmonary surfactant protein anomalies, is related to surfactant dysfunction. An important gene associated with Primary Interstitial Lung Disease Specific to Childhood Due to Pulmonary Surfactant Protein Anomalies is ABCA3 (ATP Binding Cassette Subfamily A Member 3). Affiliated tissues include lung.