Primary Mediastinal Large B-Cell Lymphoma

Alias:
Mediastinal Large B-Cell Lymphoma
Mediastinal Diffuse Large-Cell Lymphoma with Sclerosis
Primary Mediastinal Clear Cell Lymphoma of B-Cell Type
Large Cell Lymphoma of the Mediastinum
Mediastinal Large B-Cell Lymphoma
Med-Dlbcl
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Primary Mediastinal Large B-Cell Lymphoma, also known as mediastinal large b-cell lymphoma, is related to b-cell lymphoma and diffuse large b-cell lymphoma. An important gene associated with Primary Mediastinal Large B-Cell Lymphoma is BCL6 (BCL6 Transcription Repressor), and among its related pathways/superpathways are Signaling events mediated by HDAC Class I and FoxO family signaling. The drugs Vincristine and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include b cells and t cells.
Related ID:
ICD11:950282079

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Adult
1-9/100000
3
27
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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