Premature Ovarian Failure 3, also known as pof3, is related to premature menopause and premature ovarian failure 1. An important gene associated with Premature Ovarian Failure 3 is FOXL2 (Forkhead Box L2). The drugs Polyestradiol phosphate and Estradiol have been mentioned in the context of this disorder. Affiliated tissues include uterus, and related phenotypes are premature ovarian insufficiency and secondary amenorrhea