Premature Chromatid Separation Trait, also known as pcs, is related to postcholecystectomy syndrome and nondisjunction. An important gene associated with Premature Chromatid Separation Trait is BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B). Affiliated tissues include cervix, and related phenotype is premature chromatid separation.