Permanent Neonatal Diabetes Mellitus (PDMI)

Permanent Neonatal Diabetes Mellitus, also known as pndm, is related to isolated permanent neonatal diabetes mellitus and diabetes mellitus, permanent neonatal, 1, and has symptoms including seizures and muscle weakness. An important gene associated with Permanent Neonatal Diabetes Mellitus is KCNJ11 (Potassium Inwardly Rectifying Channel Subfamily J Member 11), and among its related pathways/superpathways are Nervous system development and Glucose / Energy Metabolism. The drugs Glyburide and Glucagon have been mentioned in the context of this disorder. Affiliated tissues include pancreas and pancreatic islet, and related phenotypes are shRNA abundance <= 50% and homeostasis/metabolism