Premenstrual Tension, also known as premenstrual syndrome, is related to postpartum depression and neurotic disorder, and has symptoms including pelvic pain, unspecified symptom associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4). The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include breast and skin.