Premature Menopause, also known as primary ovarian insufficiency, is related to perrault syndrome and azoospermia, and has symptoms including pelvic pain An important gene associated with Premature Menopause is STAG3 (STAG3 Cohesin Complex Component), and among its related pathways/superpathways are DNA Damage and Integrated breast cancer pathway. The drugs Norethisterone and Ganirelix have been mentioned in the context of this disorder. Affiliated tissues include ovary and bone marrow, and related phenotypes are increased circulating gonadotropin level and hypergonadotropic hypogonadism