Premature Ejaculation is related to impotence and pain disorder. An important gene associated with Premature Ejaculation is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Sudden infant death syndrome (SIDS) susceptibility pathways and Prader-Willi and Angelman syndrome. The drugs Tadalafil and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include cervix and brain.