Parkinson Disease 8, Autosomal Dominant (PARK8)

Parkinson Disease 8, Autosomal Dominant, also known as autosomal dominant parkinson disease 8, is related to early-onset parkinson's disease and parkinsonism, and has symptoms including muscle rigidity, bradykinesia and resting tremor. An important gene associated with Parkinson Disease 8, Autosomal Dominant is LRRK2 (Leucine Rich Repeat Kinase 2), and among its related pathways/superpathways are Signal Transduction and GDNF signaling. Affiliated tissues include subthalamic nucleus and olfactory bulb, and related phenotypes are hyposmia and dementia