Parkinson Disease 15, Autosomal Recessive Early-Onset (PARK15)

Parkinson Disease 15, Autosomal Recessive Early-Onset, also known as parkinsonian-pyramidal syndrome, is related to parkinson disease 1, autosomal dominant and neurodegeneration with brain iron accumulation 2a, and has symptoms including muscle rigidity, tremor and bradykinesia. An important gene associated with Parkinson Disease 15, Autosomal Recessive Early-Onset is FBXO7 (F-Box Protein 7), and among its related pathways/superpathways are Neuroscience and Autophagy. Affiliated tissues include eye and brain, and related phenotypes are abnormal pyramidal sign and parkinsonism