Parkinson Disease 14, Autosomal Recessive (PARK14)

Parkinson Disease 14, Autosomal Recessive, also known as park14, is related to neurodegeneration with brain iron accumulation 2a and neuroaxonal dystrophy, and has symptoms including muscle rigidity, muscle spasticity and tremor. An important gene associated with Parkinson Disease 14, Autosomal Recessive is PLA2G6 (Phospholipase A2 Group VI), and among its related pathways/superpathways are Glycerophospholipid biosynthesis and Ras signaling. Affiliated tissues include brain and globus pallidus, and related phenotypes are spasticity and hyperreflexia