Parkinsonism with Spasticity, X-Linked (XPDS)

Parkinsonism with Spasticity, X-Linked, also known as x-linked parkinsonism-spasticity syndrome, is related to cerebrooculofacioskeletal syndrome and xeroderma pigmentosum-cockayne syndrome complex, and has symptoms including cogwheel rigidity, bradykinesia and resting tremor. An important gene associated with Parkinsonism with Spasticity, X-Linked is ATP6AP2 (ATPase H+ Transporting Accessory Protein 2), and among its related pathways/superpathways are Regulation of TP53 Activity and DNA repair pathways, full network. Related phenotypes are cogwheel rigidity and resting tremor