Parkinsonism, also known as paralysis agitans syndrome, is related to amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 and dystonia 12. An important gene associated with Parkinsonism is GRN (Granulin Precursor), and among its related pathways/superpathways are Neuroscience and Parkinson's disease pathway. The drugs Dopamine and Amantadine have been mentioned in the context of this disorder. Affiliated tissues include brain and subthalamic nucleus, and related phenotypes are nervous system and homeostasis/metabolism