Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Recessive 1 (PEOB1)

Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Recessive 1, also known as peob1, is related to chronic progressive external ophthalmoplegia and progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1, and has symptoms including cerebellar ataxia, seizures and muscle weakness. An important gene associated with Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Recessive 1 is POLG (DNA Polymerase Gamma, Catalytic Subunit). The drugs 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and eye, and related phenotypes are visual impairment and optic atrophy