Progressive Familial Heart Block, Type Ib (PFHB1B)

Progressive Familial Heart Block, Type Ib, also known as progressive familial heart block type ib, is related to brugada syndrome 1 and progressive familial heart block, type ia, and has symptoms including syncope An important gene associated with Progressive Familial Heart Block, Type Ib is TRPM4 (Transient Receptor Potential Cation Channel Subfamily M Member 4), and among its related pathways/superpathways are G-Beta Gamma Signaling and Myometrial relaxation and contraction pathways. The drugs Acetaminophen and Atracurium have been mentioned in the context of this disorder. Affiliated tissues include heart and atrioventricular node, and related phenotypes are right bundle branch block and prolonged qt interval