Paraganglioma and Gastric Stromal Sarcoma (PGGSS)

Paraganglioma and Gastric Stromal Sarcoma, also known as carney-stratakis syndrome, is related to pheochromocytoma/paraganglioma syndrome 4 and hereditary paraganglioma-pheochromocytoma syndromes. An important gene associated with Paraganglioma and Gastric Stromal Sarcoma is SDHD (Succinate Dehydrogenase Complex Subunit D), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Glucose / Energy Metabolism. The drugs Midazolam and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include liver and skin, and related phenotypes are gastrointestinal stroma tumor and paraganglioma