Progressive Multifocal Leukoencephalopathy (PML)

Progressive Multifocal Leukoencephalopathy, also known as pml, is related to human immunodeficiency virus type 1 and acquired immunodeficiency syndrome. An important gene associated with Progressive Multifocal Leukoencephalopathy is ITGA4 (Integrin Subunit Alpha 4), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Natalizumab and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include brain and t cells, and related phenotypes are immunodeficiency and abnormality of the nervous system