Periodontitis, Aggressive, 1 (AP1)

Alias:
Pustulosis Palmaris Et Plantaris
Ppp
Localized Pustular Psoriasis
Periodontitis, Juvenile
Periodontitis, Aggressive 1
Periodontitis 1, Juvenile
Prepubertal Periodontitis
Palmoplantar Pustulosis
Jpd
Lpp
Generalized Pustular Psoriasis
Periodontititis, Aggressive, 1
Pustulosis of Palms and Soles
Periodontitis, Prepubertal
Juvenile Periodontitis
Periodontitis Juvenile
Ap1
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Periodontitis, Aggressive, 1, also known as pustulosis palmaris et plantaris, is related to psoriasis 14, pustular and periapical periodontitis. An important gene associated with Periodontitis, Aggressive, 1 is CTSC (Cathepsin C), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ixekizumab and Deucravacitinib have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are severe periodontitis and premature loss of teeth
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
AD
Unknown
--
12
123
50

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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