Periodontitis, Aggressive, 1, also known as pustulosis palmaris et plantaris, is related to psoriasis 14, pustular and periapical periodontitis. An important gene associated with Periodontitis, Aggressive, 1 is CTSC (Cathepsin C), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ixekizumab and Deucravacitinib have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are severe periodontitis and premature loss of teeth