Periodic Paralysis

Periodic Paralysis, also known as familial recurrent paralysis, is related to thyrotoxic periodic paralysis and hypokalemic periodic paralysis, type 1. An important gene associated with Periodic Paralysis is TBC1D24 (TBC1 Domain Family Member 24), and among its related pathways/superpathways are Cardiac conduction and Dopamine-DARPP32 Feedback onto cAMP Pathway. The drugs Lamotrigine and Diclofenamide have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and thyroid, and related phenotype is respiratory system.