Prediabetes Syndrome, also known as prediabetes, is related to glucose intolerance and type 1 diabetes mellitus. An important gene associated with Prediabetes Syndrome is INS (Insulin), and among its related pathways/superpathways are Signal Transduction and PI3K-Akt signaling pathway. The drugs Curcumin and Orlistat have been mentioned in the context of this disorder. Affiliated tissues include heart and pancreatic islet, and related phenotypes are homeostasis/metabolism and growth/size/body region