Periodic Limb Movement Disorder

Periodic Limb Movement Disorder, also known as nocturnal myoclonus syndrome, is related to restless legs syndrome and movement disease. An important gene associated with Periodic Limb Movement Disorder is DRD2 (Dopamine Receptor D2), and among its related pathways/superpathways are Melatonin metabolism and effects and Alpha-synuclein signaling. The drugs Iron and Iron Supplement have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and globus pallidus, and related phenotypes are nervous system and muscle