Precocious Puberty, Central, 2 (CPPB2)

Precocious Puberty, Central, 2, also known as cppb2, is related to central precocious puberty and chromosome 15q13.3 deletion syndrome. An important gene associated with Precocious Puberty, Central, 2 is MKRN3 (Makorin Ring Finger Protein 3), and among its related pathways/superpathways is Prader-Willi and Angelman syndrome. Affiliated tissues include pituitary and breast, and related phenotypes are accelerated skeletal maturation and premature pubarche