Precocious Puberty, Male-Limited (FMPP)

Alias:
Testotoxicosis
Familial Male-Limited Precocious Puberty
Fmpp
Familial Gonadotropin-Independent Male-Limited Sexual Precocity
Leydig Cell Adenoma, Somatic, with Precocious Puberty
Male-Limited Precocious Puberty
Gonadotropin-Independent Familial Sexual Precocity
Familial Testotoxicosis
Precocious Puberty
Sexual Precocity, Familial, Gonadotropin-Independent
Familial Gonadotrophin-Independent Sexual Precocity
Familial Peripheral Male-Limited Precocious Puberty
Gonadotrophin-Independent Precocious Puberty
Precocious Puberty, Male Limited
Familial Male Precocious Puberty
Precocious Puberty in Males
Testotoxicosis, Familial
Precocious Puberty, Male
Precocious Pseudopuberty
Puberty, Precocious
Pubertas Praecox
Gipp
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Precocious Puberty, Male-Limited, also known as testotoxicosis, is related to aromatase excess syndrome and juvenile type testicular granulosa cell tumor. An important gene associated with Precocious Puberty, Male-Limited is LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Megestrol acetate and Leuprolide have been mentioned in the context of this disorder. Affiliated tissues include testes and testis, and related phenotypes are precocious puberty and tall stature
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Child
<1/1000000
20
179
29

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
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IF
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