Pneumothorax, Primary Spontaneous, also known as primary spontaneous pneumothorax, is related to loeys-dietz syndrome and hemopneumothorax, and has symptoms including dyspnea and hemoptysis. An important gene associated with Pneumothorax, Primary Spontaneous is FLCN (Folliculin), and among its related pathways/superpathways are Innate Lymphoid Cells Differentiation and Development and heterogeneity of the ILC family. The drugs Diclofenac and Neostigmine have been mentioned in the context of this disorder. Affiliated tissues include lung and skin, and related phenotype is spontaneous pneumothorax.