Pancreatic and Cerebellar Agenesis (PACA)

Pancreatic and Cerebellar Agenesis, also known as permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome, is related to non-specific autoimmune cerebellar ataxia without characteristic antibodies and pancreatic cancer, and has symptoms including seizures and joint stiffness. An important gene associated with Pancreatic and Cerebellar Agenesis is PTF1A (Pancreas Associated Transcription Factor 1a). Affiliated tissues include pancreas and dorsal root ganglion, and related phenotypes are low-set ears and triangular face