Pancreatic Endocrine Carcinoma

Alias:
Malignant Neoplasm of Islets of Langerhans
Pancreatic Neuroendocrine Carcinoma
Carcinoma of Endocrine Pancreas
Carcinoma, Islet Cell
Islet Cell Carcinoma
Carcinoma Islet Cell
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Pancreatic Endocrine Carcinoma, also known as malignant neoplasm of islets of langerhans, is related to glucagonoma and hyperparathyroidism. An important gene associated with Pancreatic Endocrine Carcinoma is MEG3 (Maternally Expressed 3), and among its related pathways/superpathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). The drugs Sunitinib and Protein Kinase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include pancreas and pancreatic islet, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism
Related ID:
MESH:D018273

Basic Information

Inheritance
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Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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16
172
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Medical Symptom

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Gene & Mutation

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MGI
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References Literature

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