Pemphigus Erythematosus, also known as senear-usher syndrome, is related to pemphigus and pemphigus vulgaris, familial. An important gene associated with Pemphigus Erythematosus is DSP (Desmoplakin), and among its related pathways/superpathways are Programmed Cell Death and Keratinization. Affiliated tissues include skin and heart, and related phenotypes are autoimmunity and acantholysis