Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy 2, is also known as plosl2. An important gene associated with Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy 2 is TREM2 (Triggering Receptor Expressed On Myeloid Cells 2). Affiliated tissues include bone and thalamus, and related phenotypes are cerebral cortical atrophy and leukoencephalopathy