Polycystic Kidney Disease 2 with or Without Polycystic Liver Disease (PKD2)

Polycystic Kidney Disease 2 with or Without Polycystic Liver Disease, also known as polycystic kidney disease 2, is related to end stage renal disease and polycystic liver disease 1 with or without kidney cysts. An important gene associated with Polycystic Kidney Disease 2 with or Without Polycystic Liver Disease is PKD2 (Polycystin 2, Transient Receptor Potential Cation Channel), and among its related pathways/superpathways are Bardet-Biedl syndrome and Ciliopathies. The drugs Temsirolimus and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver, and related phenotypes are facial asymmetry and midface retrusion