Polycystic Kidney Disease 1 with or Without Polycystic Liver Disease (PKD1)

Polycystic Kidney Disease 1 with or Without Polycystic Liver Disease, also known as polycystic kidney disease 1, is related to polycystic kidney disease 2 with or without polycystic liver disease and polycystic kidney disease, infantile severe, with tuberous sclerosis. An important gene associated with Polycystic Kidney Disease 1 with or Without Polycystic Liver Disease is PKD1 (Polycystin 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways are p70S6K Signaling and Angiopoietin-like protein 8 regulatory pathway. The drugs Angiotensin II and Candesartan cilexetil have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver, and related phenotypes are mitral regurgitation and mitral valve prolapse