Polydactyly, Preaxial Iv, also known as polysyndactyly, is related to congenital heart defects, hamartomas of tongue, and polysyndactyly and tibia, hypoplasia or aplasia of, with polydactyly. An important gene associated with Polydactyly, Preaxial Iv is GLI3 (GLI Family Zinc Finger 3). The drugs Clonidine and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include bone and skin, and related phenotypes are preaxial polydactyly and 3-4 finger syndactyly