Pulmonary Hypertension (IPAH)

Alias:
Primary Pulmonary Hypertension
Idiopathic Pulmonary Arterial Hypertension
Primary Pulmonary Arterial Hypertension
Idiopathic Pulmonary Hypertension
Hypertension, Pulmonary, Primary
Pulmonary Htn - [hypertension]
Hypertension, Pulmonary
Hypertension Pulmonary
Ipah
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Pulmonary Hypertension, also known as primary pulmonary hypertension, is related to pulmonary hypertension, primary, 1 and persistent fetal circulation syndrome, and has symptoms including angina pectoris, chest pain and coughing. An important gene associated with Pulmonary Hypertension is BMPR2 (Bone Morphogenetic Protein Receptor Type 2), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and Prostaglandin synthesis and regulation. The drugs Morphine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include Lung and heart, and related phenotypes are dyspnea and pulmonary arterial hypertension
Related ID:
MESH:D006976
ICD11:1496633964

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
1-9/100000
117
1343
58

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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