Pleomorphic Rhabdomyosarcoma, also known as adult pleomorphic rhabdomyosarcoma, is related to mesenchymal cell neoplasm and leiomyosarcoma. An important gene associated with Pleomorphic Rhabdomyosarcoma is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Nervous system development and PI3K-Akt signaling pathway. The drugs Coenzyme M and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and endothelial, and related phenotypes are Increased cell migration and Synthetic lethal with vaccinia virus (VACV) infection