Pulmonary Valve Insufficiency, also known as pulmonary regurgitation, is related to infective endocarditis and carcinoid tumors, intestinal. An important gene associated with Pulmonary Valve Insufficiency is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Human Embryonic Stem Cell Pluripotency and MicroRNAs in cardiomyocyte hypertrophy. The drugs Dobutamine and Sympathomimetics have been mentioned in the context of this disorder. Affiliated tissues include heart and liver, and related phenotypes are muscle and homeostasis/metabolism