Plague, also known as yersiniosis, is related to ileitis and salmonellosis, and has symptoms including fever and pruritus. An important gene associated with Plague is CCR5 (C-C Motif Chemokine Receptor 5), and among its related pathways/superpathways are Cytokine Signaling in Immune system and NF-kappaB Signaling. The drugs Streptomycin and Ciprofloxacin have been mentioned in the context of this disorder. Affiliated tissues include lymph node and thymus, and related phenotypes are fatigue and fever