Placental Abruption

Placental Abruption, also known as abruptio placentae, is related to kidney cortex necrosis and prothrombin thrombophilia. An important gene associated with Placental Abruption is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways/superpathways are Diseases of hemostasis and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Dydrogesterone and Magnesium sulfate have been mentioned in the context of this disorder. Affiliated tissues include placenta and uterus, and related phenotypes are homeostasis/metabolism and growth/size/body region