Physical Disorder, also known as physical illness, is related to fetal alcohol spectrum disorder and orofacial cleft, and has symptoms including illness (finding) An important gene associated with Physical Disorder is CBS (Cystathionine Beta-Synthase), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and BRCA1 Pathway. The drug Antidepressive Agents has been mentioned in the context of this disorder. Affiliated tissues include lung and heart, and related phenotypes are craniofacial and skeleton