Pheochromocytoma, also known as chromaffin cell neoplasm, is related to hereditary paraganglioma-pheochromocytoma syndromes and multiple endocrine neoplasia, type iia, and has symptoms including abdominal pain, chest pain and fever. An important gene associated with Pheochromocytoma is MAX (MYC Associated Factor X), and among its related pathways/superpathways are Pyruvate metabolism and TCA cycle III (animals). The drugs Doxazosin and Phenoxybenzamine have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland and thyroid, and related phenotypes are hyperhidrosis and proteinuria